(dog-breeding) A female dog or other canine, particularly a recent mother.

“My bitch just had puppies; they're so cute!”

A promiscuous woman, slut, whore.

A despicable or disagreeable, aggressive person, usually a woman.

“Ann gossiped about me and mocked my work; sometimes she can be a real bitch!”

The lowest part of anything.

“Footers appear at the bottoms of pages.”

Character, reliability, staying power, dignity, integrity or sound judgment.

“lack bottom”

Low-lying land; a valley or hollow.

“Where shall we go for a walk? How about Ashcombe Bottom?”

A boy or younger man in a homoerotic relationship with an older man.