A sharp pinch or jerk; a twist or twitch.

“a tweak of the nose”

A slight adjustment or modification.

“He is running so many tweaks it is hard to remember how it looked originally.”

Trouble; distress; tweag.

To pinch and pull with a sudden jerk and twist; to twitch.

“to tweak the nose.”

To adjust slightly; to fine-tune.

“If we tweak the colors towards blue, it will look more natural.”

To twit or tease.