adjective

1. (of a person, thing, situation, etc.) Causing irritation, annoyance, or discomfort; bothersome, irksome.

   “My poison ivy rash is very nettlesome.”

2. (of a task, problem, etc.) Thorny; difficult to deal with, especially due to being complex or tricky.

   “Be careful what you say to him; he's a nettlesome fellow.”